Aliases
14-3-3 protein T-cell; 14-3-3 protein tau; 1433T; 143T; HS1 protein
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P27348
NCBI Gene ID: 10971
Immunogen
Synthesized peptide derived from internal of human 14-3-3 θ.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.Nielsen P.J., Biochim. Biophys. Acta 1088:425-428(1991).Leffers H., J. Mol. Biol. 231:982-998(1993).Gevaert K., Nat. Biotechnol. 21:566-569(2003).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
