Aliases
1433Z; 143Z; FAS; YWHAZ;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: P63104;
NCBI Gene#: 7534;
N
Immunogen
Peptide sequence around phosphorylation site of threonine232(S-D-T(p)-Q-G) derived from Human 14-3-3 zeta/ delta .
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:1000
Background / Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.Sluchanko NN, et al. (2011) Arch Biochem Biophys 506, 24-34 Sluchanko NN, et al. (2008) Arch Biochem Biophys 477, 305-12 Clokie SJ, et al. (2005) FEBS J 272, 3767-76
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Thr232
