Description
Aliases
Tegument protein VP16, Alpha trans-inducing protein, Alpha-TIF, ICP25, Vmw65, UL48
Antibody Type
Polyclonal Antibody
Species
Human herpesvirus 1
Uniprot ID
P04486
Immunogen
Recombinant human herpesvirus 1 Tegument protein VP16 protein (1-490AA)
Raised In
Rabbit
Species Reactivity
Human herpesvirus 1
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Additional information
Size | 50μg, 100μg |
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