Aliases
Protein EnvA, UDP-3-O-acyl-GlcNAc deacetylase, lpxC, asmB, envA, b0096, JW0094
Antibody Type
Polyclonal Antibody
Species
Escherichia coli
Uniprot ID
P0A725
Immunogen
Recombinant Escherichia coli UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase protein (1-305AA)
Raised In
Rabbit
Species Reactivity
Escherichia coli
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
The key enzyme in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Degraded by FtsH; when the activity of FtsH is reduced too much lipid A and not enough phospholipids are made (both pathways use the same precursor), which is lethal.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]Sequence analysis, transcriptional organization, and insertional mutagenesis of the envA gene of Escherichia coli.Beall B., Lutkenhaus J.J. Bacteriol. 169:5408-5415(1987) [2]Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4
