Aliases
Holliday junction ATP-dependent DNA helicase RuvA, ruvA
Antibody Type
Polyclonal Antibody
Species
Escherichia coli
Uniprot ID
P0A809
Immunogen
Recombinant Escherichia coli Holliday junction ATP-dependent DNA helicase RuvA protein (1-203AA)
Raised In
Rabbit
Species Reactivity
Escherichia coli
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Binds both single- and double-stranded DNA (dsDNA). Binds preferentially to supercoiled rather than to relaxed dsDNA.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
