Description
Aliases
Dermonecrotic toxin, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D, PLD
Antibody Type
Polyclonal Antibody
Species
Loxosceles amazonica
Uniprot ID
C0JAZ9
Immunogen
Recombinant Loxosceles amazonica Phospholipase D LamSicTox-alphaIC1 protein (1-273AA)
Raised In
Rabbit
Species Reactivity
Loxosceles amazonica
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Catalyzes the hydrolysis of sphingomyelin. May also acts on other phosphatidyl esters. Induces complement-dependent hemolysis, dermonecrosis, blood vessel permeability and platelet aggregation.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]Molecular evolution, functional variation, and proposed nomenclature of the gene family that includes sphingomyelinase D in sicariid spider venoms. Binford G.J., Bodner M.R., Cordes M.H., Baldwin K.L., Rynerson M.R., Burns S.N., Zobel-Thropp P.A. Mol. Biol. Evol. 26:547-566(2009).Additional information
Size | 50μg, 100μg |
---|