Description
Aliases
DRP-1, Collapsin response mediator protein 1, CRMP-1, Unc-33-like phosphoprotein 3, ULIP-3, DPYSL1, ULIP3, CRMP1
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q14194
Immunogen
Recombinant human Dihydropyrimidinase-related protein 1 protein (1-572AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May participate in cytokinesis.
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Dihydropyrimidinase-related protein 1 protein
Literature
[1]”From midbody protein-protein interaction network construction to novel regulators in cytokinesis.” Chen T.C., Lee S.A., Hong T.M., Shih J.Y., Lai J.M., Chiou H.Y., Yang S.C., Chan C.H., Kao C.Y., Yang P.C., Huang C.Y. J. Proteome Res. 8:4943-4953(2009). [2]”Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells.” Shih J.-Y., Yang S.-C., Hong T.-M., Yuan A., Chen J.J.W., Yu C.-J., Chang Y.-L., Lee Y.-C., Peck K., Wu C.-W., Yang P.-C. J. Natl. Cancer Inst. 93:1392-1400(2001). [3]”Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase.” Wang L.H., Strittmatter S.M. J. Neurochem. 69:2261-2269(1997).Additional information
Size | 50μg, 100μg |
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