Description
Aliases
CD158 antigen-like family member H, MHC class I NK cell receptor Eb6 ActI, CD158h, KIR2DS1
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q14954
Immunogen
Recombinant human Killer cell immunoglobulin-like receptor 2DS1 protein (22-245AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Killer cell immunoglobulin-like receptor 2DS1
Literature
[1]”The DNA sequence and biology of human chromosome 19.” Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V. Lucas S.M. Nature 428:529-535(2004). [2]”Human diversity in killer cell inhibitory receptor genes.” Uhrberg M., Valiante N.M., Shum B.P., Shilling H.G., Lienert-Weidenbach K., Corliss B., Tyan D., Lanier L.L., Parham P. Immunity 7:753-763(1997). [3]”The human leukocyte antigen (HLA)-C-specific ‘activatory’ or ‘inhibitory’ natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.” Biassoni R., Cantoni C., Falco M., Verdiani S., Bottino C., Vitale M., Conte R., Poggi A., Moretta A., Moretta L. J. Exp. Med. 183:645-650(1996).Additional information
| Size | 50μg, 100μg |
|---|
