Aliases
Atlastin-3, ATL3
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q6DD88
Immunogen
Recombinant human Atlastin-3 protein (1-187AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, WB, IHC, IF;Recommended dilution:WB:1:500-2000, IHC:1:20-1:200, IF:1:50-1:200
Background / Function
GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]”Cellular localization, oligomerization, and membrane association of the hereditary spastic paraplegia 3A (SPG3A) protein atlastin.”Zhu P.-P., Patterson A., Lavoie B., Stadler J., Shoeb M., Patel R., Blackstone C.J. Biol. Chem. 278:49063-49071(2003). [2]”Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.”Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.Cell 127:635-648(2006). [3]”A class of dynamin-like GTPases involved in the generation of the tubular ER network.”Hu J., Shibata Y., Zhu P.-P., Voss C., Rismanchi N., Prinz W.A., Rapoport T.A., Blackstone C.Cell 138:549-561(2009).
