Aliases
Cap-specific mRNA (nucleoside-2′-O-)-methyltransferase 2 (EC:2.1.1.296), CMTR2, AFT, FTSJD1, Cap methyltransferase 2, Cap2 2’O-ribose methyltransferase 2, HMTr2, MTr2, FtsJ methyltransferase domain-containing protein 1, Protein adrift homolog
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q8IYT2
Immunogen
Recombinant human Cap-specific mRNA (nucleoside-2′-O-)-methyltransferase 2 protein (301-600AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2′-O-ribose methylation to the 5′-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
