Description
Aliases
Protein DBF4 homolog B, DBF4B, ASKL1, DRF1, Activator of S phase kinase-like protein 1, ASK-like protein 1, Chiffon homolog B, Dbf4-related factor 1
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q8NFT6
Immunogen
Recombinant human Protein DBF4 homolog B protein (1-300AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at ‘Ser-40’ and then is involved in regulating the initiation of DNA replication during cell cycle.
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Additional information
| Size | 50μg, 100μg |
|---|
