Description
Aliases
Cep83, Cep83, Renal carcinoma antigen NY-REN-58, CEP83, CCDC41
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q9Y592
Immunogen
Recombinant human Centrosomal protein of 83 kDa protein (1-568AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium during the initiation of primary cilium assembly.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]Mutations of CEP83 cause infantile nephronophthisis and intellectual disability.Failler M., Gee H.Y., Krug P., Joo K., Halbritter J., Belkacem L., Filhol E., Porath J.D., Braun D.A., Schueler M., Frigo A., Alibeu O., Masson C., Brochard K., Hurault de Ligny B., Novo R., Pietrement C., Kayserili H. Saunier S.Am. J. Hum. Genet. 94:905-914(2014). [2]CCDC41 is required for ciliary vesicle docking to the mother centriole.Joo K., Kim C.G., Lee M.S., Moon H.Y., Lee S.H., Kim M.J., Kweon H.S., Park W.Y., Kim C.H., Gleeson J.G., Kim J.Proc. Natl. Acad. Sci. U.S.A. 110:5987-5992(2013) .Additional information
| Size | 50μg, 100μg |
|---|
