Aliases
T-lymphoma invasion and metastasis-inducing protein 1TIAM-1, TIAM1
Antibody Type
Polyclonal
Species
Human
Uniprot ID
Q13009
Immunogen
Recombinant human T-lymphoma invasion and metastasis-inducing protein 1 protein (52-224AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Modification
T-lymphoma invasion and metastasis-inducing protein 1
