Aliases
Homeobox protein TGIF1, 5′-TG-3′-interacting factor 1, TGIF1, TGIF
Antibody Type
Polyclonal
Species
Human
Uniprot ID
Q15583
Immunogen
Recombinant Human Homeobox protein TGIF1 protein (8-375AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA
Background / Function
Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Modification
Homeobox protein TGIF1