Aliases
vacuole membrane protein 1
Antibody Type
Polyclonal Antibody
Uniprot ID
Q96GC9
Immunogen
Synthetic peptide of human VMP1
Raised In
Rabbit
Species Reactivity
Human, Mouse, Rat
Tested Applications
ELISA: 1:1000-1:2000; WB:1:200-1:1000; IHC: 1:25-1:100
Background / Function
VMP1 (Vacuole membrane protein 1), is a 406 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum-golgi intermediate compartment membrane. Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen affinity purification
