Aliases
forkhead box J3
Antibody Type
Polyclonal Antibody
Uniprot ID
Genbank No.: NP_055762
Immunogen
Synthetic peptide corresponding to a region derived from 610-622 amino acids of Human forkhead box J1
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
ELISA WB Recommended dilution: Predicted MW: 69kd, ELISA: 1:1000-1:5000, Western blotting: 1:2000-1:5000
Background / Function
forkhead/winged helix transcription factor, Foxj3, which was expressed in embryonic and adult skeletal muscle. The 100-kb, 13-exon mouse Foxj3 gene on chromosome 4 encodes a 623 amino acid (aa) protein from an mRNA of at least 4.8 kb (Human FOXJ3: Chr 1, 627 aa, 5.3-kb mRNA). During the stages of mouse development investigated Foxj3 is expressed in neuroectoderm, in neural crest, and in many structures derived from neural crest cells, such as facioacoustic, trigeminal, and dorsal root ganglia. Stripes of expression appear at E10.5 in the location of myotomes and expand ventrally in a pattern similar to the developing body wall musculature. Developing limbs have a complex pattern of Foxj3 expression that at E12.5 colocalizes with the condensed mesenchyme of the skeletal primordia.
Conjugate
Unconjugated
Storage Buffer
Supplied at 0.5mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
