Aliases
Max-associated protein 4; MAX dimerization protein 4;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q14582
NCBI Gene ID: 10608
Immunogen
Synthesized peptide derived from internal of human MAD4.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
IHC Recommended dilution: Immunohistochemistry: 1:50~1:100
Background / Function
Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5′-CAC[GA]TG-3′. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation By similarity.Hillier L.W., Nature 434:724-731(2005).The MGC Project Team, Genome Res. 14:2121-2127(2004).Pribill I., Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
