Aliases
5-HT6; 5HT6R; HTR6;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P50406
NCBI Gene ID: 3362
Immunogen
Synthesized peptide derived from internal of human 5-HT-6.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.Kohen R., J. Neurochem. 66:47-56(1996).Kopatz S.A., Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.Gregory S.G., Nature 441:315-321(2006).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
