Aliases
Carboxylesterase 2; carboxylesterase 2 (intestine; liver); CE-2; CES2
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: O00748
NCBI Gene ID: 8824
Immunogen
Synthesized peptide derived from Internal of human CES2.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine.Schwer H., Biochem. Biophys. Res. Commun. 233:117-120(1997).Pindel E.V., J. Biol. Chem. 272:14769-14775(1997).Sone T., Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
