Aliases
Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58 antigen;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P19256
NCBI Gene ID: 965
Immunogen
Synthesized peptide derived from internal of human LFA3.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.Wallner B.P., J. Exp. Med. 166:923-932(1987).Wallich R., J. Immunol. 160:2862-2871(1998).Ota T., Nat. Genet. 36:40-45(2004).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
