Aliases
P21 protein (Cdc42/Rac)-activated kinase 1, PAKalpha
Antibody Type
Polyclonal Antibody
Uniprot ID
Genbank No.: NP_001122092
Immunogen
Synthetic peptide corresponding to a region derived from 225-238 amino acids of Human p21 protein (Cdc42/Rac)-activated kinase
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
ELISA WB IHC Recommended dilution: Predicted MW: 61kd, ELISA: 1:1000-1:5000, Western blotting: 1:500-1:2000, Immunohistochemistry: 1:25-1:100
Background / Function
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.4mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
