Aliases
COUP transcription factor 2; COUP-TF2; COUP-TF II; Nuclear receptor subfamily 2 group F member 2; Apolipoprotein AI regulatory protein 1
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P24468
NCBI Gene ID: 7026
Immunogen
Synthesized peptide derived from N-terminal of human COT2.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IF Recommended dilution: Western blotting: 1:500~1:3000Immunofluorescence: 1:100~1:500
Background / Function
Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.Ladias J.A.A., Science 251:561-565(1991).The MGC Project Team, Genome Res. 14:2121-2127(2004).Wang L.H., Gene Expr. 1:207-216(1991).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
