Aliases
5-hydroxytryptamine receptor 4; 5-HT-4; Serotonin receptor 4; 5-HT4; HTR4
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q13639
NCBI Gene ID: 3360
Immunogen
Synthesized peptide derived from internal of human 5-HT-4.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IF Recommended dilution: Western blotting: 1:500~1:3000Immunofluorescence: 1:100~1:500
Background / Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.Blondel O., J. Neurochem. 70:2252-2261(1998).Claeysen S., NeuroReport 8:3189-3195(1997).Claeysen S., Mol. Pharmacol. 55:910-920(1999).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
