Aliases
GDAIF
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: O14514
NCBI Gene ID: 575
Gene
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human brain-specific angiogenesis inhibitor 1
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
IHC Recommended dilution: Immunohistochemistry: 1:50-1:200
Background / Function
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one ‘functional’ p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
