Aliases
Protein-tyrosine phosphatase 2C
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q06124
NCBI Protein: NP_002825.3
Immunogen
Peptide sequence around aa.578~582 (R-V-Y-E-N) derived from Human SHP-2.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IHC IF Recommended dilution: Predicted MW: 72kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background / Function
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.Ferjoux G, et al. (2003) Mol Biol Cell. 2003; 14(9): 3911-3928.Shi ZQ, et al. (2000) Mol Cell Biol ; 20(5): 1526-1536.
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
