Description
Aliases
H3 histone antibody; HIST1H3A antibody; Histone cluster 1; H3a antibody
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#:P68431
Immunogen
Peptide sequence around phosphorylation site of threonine 118(R-V-T(p)-I-M) derived from Human Histone H3.
Raised In
Rabbit
Species Reactivity
Human Rat Mouse
Tested Applications
WB Recommended dilution: Western blotting: 1:1000,
Background / Function
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Conjugate
Unconjugated
Storage Buffer
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Thr118
Additional information
| Size | 100μl |
|---|
