PGK1 Antibody, Biotin conjugated

Description

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P00558

Immunogen

Recombinant human Phosphoglycerate kinase 1 protein (25-417AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Also known as ATP:3-phosphoglycerate 1-phosphotransferase, this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. In addition to its role as a glycolytic enzyme, PGK-1 appears to acts as a polymerase alpha cofactor protein. Defects in PGK1 are generally associated with chronic hemolytic anemia.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Phosphoglycerate kinase 1 protein

Research

Metabolism

Literature

[1] “Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase.”Michelson A.M., Markham A.F., Orkin S.H.Proc. Natl. Acad. Sci. U.S.A. 80:472-476(1983) [2] “Structure of the human phosphoglycerate kina

Additional information

Size	50μg, 100μg