Description
Aliases
Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, SSADH, ALDH5A1
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P51649
Immunogen
Recombinant human Succinate-semialdehyde dehydrogenase, mitochondrial protein (48-535AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Succinate-semialdehyde dehydrogenase, mitochondrial
Literature
[1]”Redox-switch modulation of human SSADH by dynamic catalytic loop.” Kim Y.-G., Lee S., Kwon O.-S., Park S.-Y., Lee S.-J., Park B.-J., Kim K.-J. EMBO J. 28:959-968(2009). [2]”Human succinic semialdehyde dehydrogenase. Molecular cloning and chromosomal localization.” Trettel F., Malaspina P., Jodice C., Novelletto A., Slaughter C.A., Caudle D.L., Hinson D.D., Chambliss K.L., Gibson K.M. Adv. Exp. Med. Biol. 414:253-260(1997). [3]”Molecular cloning of the mature NAD(+)-dependent succinic semialdehyde dehydrogenase from rat and human. cDNA isolation, evolutionary homology, and tissue expression.” Chambliss K.L., Caudle D.L., Hinson D.D., Moomaw C.R., Slaughter C.A., Jakobs C., Gibson K.M. J. Biol. Chem. 270:461-467(1995).Additional information
| Size | 50μg, 100μg |
|---|
