Description
Aliases
Aspartate beta-hydroxylase Peptide-aspartate beta-dioxygenase ASPH
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q12797
Immunogen
Recombinant human Aspartyl/asparaginyl beta-hydroxylase protein (75-270AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Isoform 1:specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins. Ref.13 Isoform 8:membrane-bound Ca2+-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Signal Transduction
Literature
[1]Cloning and characterization of the human gene encoding aspartyl beta-hydroxylase.Korioth F., Gieffers C., Frey J.Gene 150:395-399(1994) [2]Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcinoAdditional information
Size | 50μg, 100μg |
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