Description
Aliases
Branched-chain-amino-acid aminotransferase, mitochondrial, Placental protein 18, BCATM, BCT2, ECA40, BCAT2
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
O15382
Immunogen
Recombinant human Branched-chain-amino-acid aminotransferase, mitochondrial (28-392AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Epigenetics and Nuclear Signaling
Literature
[1]”Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis.”Yennawar N.H., Islam M.M., Conway M., Wallin R., Hutson S.M.J. Biol. Chem. 281:39660-39671(2006). [2]”Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin.” Goto M., Miyahara I., Hirotsu K., Conway M., Yennawar N., Islam M.M., Hutson S.M.J. Biol. Chem. 280:37246-37256(2005). [3]”Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms.”Yennawar N.H., Conway M.E., Yennawar H.P., Farber G.K., Hutson S.M.Biochemistry 41:11592-11601(2002).Additional information
| Size | 50μg, 100μg |
|---|
