Aliases
N-glycosylase/DNA lyaseIncluding the following 2 domains:8-oxoguanine DNA glycosylase (EC:3.2.2.-)DNA-(apurinic or apyrimidinic site) lyase (EC:4.2.99.18), AP lyase, OGG1, MMH, MUTM, OGH1
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
O15527
Immunogen
Recombinant human N-glycosylase/DNA lyase protein (1-345AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3′ to the lesion.
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
