Aliases
Eosinophil-derived neurotoxin, RNase UpI-2, Ribonuclease 2, Ribonuclease US, RNASE2, EDN, RNS2
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P10153
Immunogen
Recombinant human Non-secretory ribonuclease protein (28-161AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Immunology
Literature
[1] “Sequence of human eosinophil-derived neurotoxin cDNA: identity of deduced amino acid sequence with human nonsecretory ribonucleases.”Hamann K.J., Barker R.L., Loegering D.A., Pease L.R., Gleich G.J.Gene 83:161-167(1989) [2] “Eosinophil cationic pro