Aliases
Aromatic esterase 1, K-45, Serum aryldialkylphosphatase 1, PON1, PON
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P27169
Immunogen
Recombinant Human Serum paraoxonase/arylesterase 1 protein (2-355AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Cardiovascular
Literature
[1]Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence.Hassett C., Richter R.J., Humbert R., Chapline C., Crabb J.W., Omiecinski C.J., Furlong C.E.Biochemistry 30:10141-10149(1991)
