Aliases
C/EBP-homologous protein, DDIT3, DNA-damage inducible transcript 3, GADD153, Growth arrest and DNA-damage-inducible protein GADD153 Molecular weight: 19174.8 chop
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: P35638
Immunogen
A synthesized peptide derived from human GADD153
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IHC IF/ICC Recommended dilution: WB: 1:500-1:2000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500
Background / Function
CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
