Description
Aliases
alpha-fetoprotein, FETA, HPAFP
Antibody Type
Polyclonal Antibody
Uniprot ID
P02771
Immunogen
Fusion protein corresponding to a region derived from 260-609 amino acids of human alpha-fetoprotein
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
ELISA WB IHC Recommended dilution: Predicted MW: 69kd, ELISA: 1:2000-1:10000, Western blotting: 1:1000-1:5000, Immunohistochemistry: 1:50-1:200
Background / Function
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Conjugate
Unconjugated
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Additional information
| Size | 100μl, 50μg, 100μg |
|---|
