Description
Aliases
Proliferating cell nuclear antigen
Antibody Type
Polyclonal Antibody
Uniprot ID
P12004
Immunogen
Fusion protein corresponding to a region derived from 9-252 amino acids of Human Proliferating cell nuclear antigen
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
ELISA WB IHC Recommended dilution: Predicted MW: 29kd, ELISA: 1:500-1:5000, Western blotting: 1:500-1:2000, Immunohistochemistry: 1:25-1:100
Background / Function
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome
Conjugate
Unconjugated
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Additional information
| Size | 100μl, 50μg, 100μg |
|---|
