Description
Aliases
PAR-1, Coagulation factor II receptor, Thrombin receptor, F2R, CF2R, PAR1, TR
Antibody Type
Polyclonal Antibody
Uniprot ID
P25116
Immunogen
Synthetic peptide corresponding to a region derived from 56-70 amino acids of human coagulation factor II (thrombin) receptor
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, WB, IHC;Recommended dilution:WB:1:500-2000, IHC:1:50-1:200
Background / Function
Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.3mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
Additional information
| Size | 100μl, 50μg, 100μg |
|---|
