Description
Aliases
Cancer-associated retinopathy protein, RCV1, RCVRN
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P35243
Immunogen
Recombinant human Recoverin protein (2-200AA)
Raised In
Rabbit
Species Reactivity
Human,Mouse
Tested Applications
ELISA, WB
Background / Function
Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Recoverin
Literature
[1]”Crystal structure of human recoverin at 2.2 A resolution.” RIKEN structural genomics initiative (RSGI) Submitted (FEB-2007). [2]”A photoreceptor calcium binding protein is recognized by autoantibodies obtained from patients with cancer-associated retinopathy.” Polans A.S., Buczylko J., Crabb J., Palczewski K. J. Cell Biol. 112:981-989(1991). [3]”Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.” Oshikawa M., Tsutsui C., Ikegami T., Fuchida Y., Matsubara M., Toyama S., Usami R., Ohtoko K., Kato S. Invest. Ophthalmol. Vis. Sci. 52:6662-6670(2011).Additional information
Size | 50μg, 100μg |
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