Aliases
ATP-binding cassette sub-family B member 1, P-glycoprotein 1, CD_antigen=CD243, ABCB1, MDR1, PGY1
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P08183
Immunogen
Recombinant human Multidrug resistance protein 1 protein (236-297AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Multidrug resistance protein 1 protein
Research
Transport
Literature
[1] “Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.”Chen C.-J., Chin J.E., Ueda K., Clark D.P., Pastan I., Gottesman M.M., Roninson I.B.Cell 47:381-389(1986) [2
