Aliases
Transcriptional adapter 2-like; ADA2-like protein; TADA2L; KL04P;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: O75478
NCBI Gene ID: 6871
Immunogen
Synthesized peptide derived from internal of human ADA2L.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site By similarity. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.Candau R., Mol. Cell. Biol. 16:593-602(1996).Ogryzko V.V., Cell 94:35-44(1998).Henriksson A., Mol. Cell. Biol. 17:3065-3073(1997).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
