Aliases
Protein AF-10; MLLT10; AF10;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P55197
NCBI Gene ID: 8028
Immunogen
Synthesized peptide derived from internal of human AF10.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA.Chaplin T., Blood 85:1435-1441(1995).Deloukas P., Nature 429:375-381(2004).Matsuoka S., Science 316:1160-1166(2007).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.