Description
Aliases
AK 1, ATP-AMP transphosphorylase 1, ATP:AMP phosphotransferase, Adenylate monophosphate kinase, Myokinase, AK1
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P00568
Immunogen
Recombinant human Adenylate kinase isoenzyme 1 protein (1-194AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Adenylate kinase isoenzyme 1
Literature
[1]”Red cell adenylate kinase deficiency: molecular study of 3 new mutations (118G>A, 190G>A, and GAC deletion) associated with hereditary nonspherocytic hemolytic anemia.” Corrons J.-L., Garcia E., Tusell J.J., Varughese K.I., West C., Beutler E. Blood 102:353-356(2003). [2]”Severe erythrocyte adenylate kinase deficiency due to homozygous A–>G substitution at codon 164 of human AK1 gene associated with chronic haemolytic anaemia.” Qualtieri A., Pedace V., Bisconte M.G., Bria M., Gulino B., Andreoli V., Brancati C. Br. J. Haematol. 99:770-776(1997). [3]”Crystal structure of human AK1A in complex with AP5A.” Structural genomics consortium (SGC) Submitted (MAR-2007).Additional information
| Size | 50μg, 100μg |
|---|
