Aliases
15-lipooxygenase-1; 15-LOX; 15-LOX-1; 15LOX-1; ALOX15;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: Q5RBE8 Immunogen Synthetic peptide corresponding to residues near the C terminal of human arachidonate 15-lipoxygenase Raised In Rabbit Species Reactivity Human Mouse Rat Tested Applications WB IHC Recommended dilution: Western blotting: 1:1000-1:5000, Immunohistochemistry: 1:50-1:200 Background / Function Arachidonate 15-lipoxygenase is an enzyme that in humans is encoded by the ALOX15 gene. The ALOX15 gene maps to 17p13.3 in close proximity to the tumor-suppressor gene TP53. The ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Conjugate Unconjugated Storage Buffer Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. Form liquid Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze. Purity Antigen Affinity Purified
NCBI Gene ID: 100174413
