Aliases
AMZ1; Archaemetzincin-1; KIAA1950;metalloproteinase-like protein
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: Q400G9
NCBI Gene ID: 155185
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human archaelysin family metallopeptidase 1
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IHC Recommended dilution: Western blotting: 1:500-1:2000, Immunohistochemistry: 1:50-1:200
Background / Function
AMZ1 shares sequence similarity with archaeal metalloproteases called archaemetzincins, but it appears to act predominantly as a basic aminopeptidase. Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
