ASPH Antibody, Biotin conjugated

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Description

Aliases

Aspartate beta-hydroxylase Peptide-aspartate beta-dioxygenase ASPH

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

Q12797

Immunogen

Recombinant human Aspartyl/asparaginyl beta-hydroxylase protein (75-270AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Isoform 1:specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins. Ref.13 Isoform 8:membrane-bound Ca2+-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Signal Transduction

Literature

[1]Cloning and characterization of the human gene encoding aspartyl beta-hydroxylase.Korioth F., Gieffers C., Frey J.Gene 150:395-399(1994) [2]Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcino

Additional information

Size

50μg, 100μg

Certificate of Analysis