Description
Aliases
Bcl-10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, cCARMEN, Cellular-E10, c-E10, mE10, BCL10, CIPER, CLAP
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
O95999
Immunogen
Recombinant human B-cell lymphoma/leukemia 10 protein (1-233AA)
Raised In
Rabbit
Species Reactivity
human
Tested Applications
ELISA, IHC;Recommended dilution:IHC:1:20-1:200
Background / Function
Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Apoptosis
Literature
[1]”Absence of BCL10 mutations in human malignant mesothelioma.”Apostolou S., de Rienzo A., Murthy S.S., Jhanwar S.C., Testa J.R.Cell 97:684-686(1999). [2]”System-wide temporal characterization of the proteome and phosphoproteome of humAdditional information
| Size | 50μg, 100μg, 50μl, 100μl |
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