BCL10 Antibody, Biotin conjugated

Description

Aliases

Bcl-10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, cCARMEN, Cellular-E10, c-E10, mE10, BCL10, CIPER, CLAP

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

O95999

Immunogen

Recombinant human B-cell lymphoma/leukemia 10 protein (1-233AA)

Raised In

Rabbit

Species Reactivity

human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Apoptosis

Literature

[1]”Absence of BCL10 mutations in human malignant mesothelioma.”Apostolou S., de Rienzo A., Murthy S.S., Jhanwar S.C., Testa J.R.Cell 97:684-686(1999). [2]”System-wide temporal characterization of the proteome and phosphoproteome of hum

Additional information

Size	50μg, 100μg