Caspase 5, Human Recombinant
General description
Caspase-5 (also known as ICErelIII, TY) is a member of the caspase-family of cysteine proteases. Similar to other caspases, Caspase-5 exists in cells as an inactive proenzyme which is matured by proteolysis to yield large and small subunits. The active Caspase-5 is a heterotetrametric molecule consisting of two large and two small subunits. To date the mechanism of Caspase-5 activation and roles of Caspase-5 in apoptosis are poorly understood. The recombinant active human Caspase-5 was expressed in E. coli.
Synonyms:Â Â Â Â Â Â Â Â Â Â Â Â Caspase-5, CASP-5, ICE (rel)-III, Protease ICH-3, Protease TY
Gene Symbol:Â Â Â Â Â Â Â Â Â CASP5
Gene ID:Â Â Â Â Â Â Â Â Â Â Â Â Â Â 838
Source:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â E. coli.
Form:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Lyophilized powder
Reconstitution Inst:       Reconstitute to 1 unit per µl in PBS containing 15% glycerol
Handling:Â Â Â Â Â Â Â Â Â Â Â Â Â Centrifuge the vial prior to opening
Storage temp.:         -70°C
