Caspase General Inhibitor, fluoromethyl ketone, FMK
General description
This product is a synthetic peptide that irreversibly inhibits activity of caspase family proteases and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability. It can be used in both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Synonyms:Â Â Â Â Â Â Â Â Â Â Â Â Z-VAD-FMK, Z-VAD fluoromethylketone, Caspase-Family Inhibitor, pan-caspase inhibitor
Peptide Sequence:Â Â Â Â Â Z-Val-Ala-Asp (OMe)-FMK
Appearance:Â Â Â Â Â Â Â Â Â Â Â Liquid
Formulation:Â Â Â Â Â Â Â Â Â Â 1010-100 In DMSO (2 mM); 1010-20C In DMSO (10 mM)
Molecular Formula:       C₂₂H₃₀N₃O₇F
Molecular Weight:Â Â Â Â Â Â 467.5
InChi Key:Â Â Â Â Â Â Â Â Â Â Â Â Â MIFGOLAMNLSLGH-UHFFFAOYSA-N
PubChem CID:Â Â Â Â Â Â Â Â Â 5737
Handling:Â Â Â Â Â Â Â Â Â Â Â Â Â Protect from light and moisture
Storage temp.:         -20°C