Aliases
Coiled-coil domain-containing protein 8, CCDC8
Antibody Type
Polyclonal
Species
Human
Uniprot ID
Q9H0W5
Immunogen
Recombinant human Coiled-coil domain-containing protein 8 protein (214-513AA)
Raised In
Rabbit
Species Reactivity
Human,mouse
Tested Applications
ELISA, WB, IF;Recommended dilution:WB:1:2000-1:5000, IF:1:50-1:200
Background / Function
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Required for localization of CUL7 to the centrosome (PubMed:24793695).
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Modification
Coiled-coil domain-containing protein 8